Breakthroughs against malaria: highly effective vaccine developed

Scientific Forefront

This Anopheles gambiae mosquito is obtaining a blood meal as it feeds on a human host.  Credit: CDC/Jim Gathany

Some 300 million cases of malaria are reported each year in Africa, the continent where the disease is still running rampant. For decades, scientists have been investing immense amounts of energy battling the disease, trying to come up with effective treatments. The recent step forward in the war against malaria comes from Maryland-based biotech Sanaria, which reportedly has developed an anti-malaria vaccine with promising results to boast from a phase 1 clinical trial.
To make the vaccine, the researchers first irradiated parasite-infected mosquitoes, harvesting weakened parasites from the mosquitoes’ salivary glands, and then cryopreserving them. The idea that irradiated mosquitoes might be used for anti-malaria infection purposes isn’t new. Since the 1970′s it was shown that bites from irradiated, malaria-infected mosquitoes appeared to protect people from the disease, however at the time it was difficult to isolate large quantities of whole, irradiated parasites.

Full Story

View original post

Advertisements

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s